This means that the URL in question has at least one outgoing hreflang annotation which is canonicalized to another URL.
Hreflang tags are interpreted by search engines as indexing instructions. An English page that has hreflang pointing at its French alternate is instructing search engines to index both the English version and the French version, and to consider each as equivalent in their respective languages.
If this French page was canonicalized to another URL (for argument's sake, we'll call it a Canadian page) then this would be an instruction to not index the French page, and to instead index the Canadian page.
So the hreflang is saying 'please index the French page', and the canonical is saying 'don't index the French page.'
This type of conflicting instruction serves to confuse search engines, to the point where they will ignore the canonical and/or hreflang, and make up their own mind about which are the right URLs to index.
This Hint will trigger for any URL which contains hreflang annotations, where at least one of the hreflang URLs is canonicalized.
Note: This Hint is very similar to another Hint: Canonicalized URL has incoming hreflang. The difference being that this Hint is analysing the page with hreflang on (i.e. outgoing hreflang) whereas the other Hint is analysing the target page of a hreflang annotation (i.e. incoming hreflang).
Consider the URL: https://example.com/page-a/
The Hint would trigger for this URL if it included an hreflang annotation:
<link rel="alternate" href="https://example.com/us/page-a/" hreflang="en-us" />
where this hreflang page had a canonical tag that is not self-referential:
<link rel="canonical" href="https://example.com/us/page-b/" />
The problem with this sort of conflicting instruction is that it is not instantly obvious which page is causing the error. Either the hreflang is wrong or the canonical is wrong. This is what will cause search engines to guess, and they may not guess correctly.
The best solution is take the situation into your control, so that they do not need to guess. And this starts with figuring out which is the correct hreflang URL, which may require manual inspection.
Once you have established this, it should be straightforward to work out the next step:
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